Critical Care Research Festival

A study being run in the CRF in critically ill patients aged 65 years or over with vasodilatory hypotension was on the agenda at the Critical Care Research Festival on 19th January 2018.

 The Festival, which took place at the Northern General Hospital involved an overview of Sheffield Teaching Hospitals research in Critical Care, short presentations on trials run in Sheffield, posters and informal drop in sessions 

(Jan 2018)

Sheffield Biomedical Research Centre Public Launch Event  

On the 14 December the Sheffield Institute for Translational Neuroscience (SITraN) hosted the public launch event of the NIHR Biomedical Research Centre (BRC) for Translational Neuroscience.

The Sheffield BRC is focused on pulling through translational discoveries into early phase and experimental medicine studies to improve the lives of people living with chronic neurological disorders.

Click here to read more

(December 2017)

Sheffield Tops League Table for Recruitment into Lung Disease Study

Respiratory researchers working with the CRF to deliver a lung disease trial have been announced by the research sponsor as the top UK recruiter from six UK hospitals which were also participating in the trial. 

Sheffield recruited 6 patients into the clinical trial.

CRF Orange Team clinical research nurses Michael and Faith are pictured with the Principal Investigator for the study, Dr Bianchi at the Northern General Hospital CRF.

For information on clinical research studies available to participate in nationwide please visit the UK Clinical Trials Gateway at

(October 2017)

Sheffield Teaching Hospitals named as top ten UK NHS Research Trust

Patients at Sheffield Teaching Hospitals NHS Foundation Trust have some of the best access to medical research according to a national league table. Sheffield Teaching Hospitals NHS Foundation Trust has been named as a UK top ten NHS ‎research active Trust.

Between 2016 and 2017 11,490 patients took part in clinical research trials at Sheffield's five adult hospitals, a 34% increase from the previous year. Commercially, the Trust had the second-highest number of studies recruited to in the Yorkshire and Humber region, with 69, a 23% rise. A total of 335 participants were involved in these studies, an increase of 31% on last year's 256. The Trust also ran 10% more academically led studies across a wide range of disease areas. Click here to read more.

(July 2017)

Good Luck for the Nursing Times Awards!

Following the success of recent clinical trials for the treatment of atopic dermatitis, lead CRF nurse Maqsood Khan has submitted an application for the Nursing Times Awards 2017. Maqsood was instrumental in the delivery of 4 phase 3 studies that transformed the lives of patients who had exhausted all other means of treating their condition.

The NIHR Sheffield CRF Dupilumab research team from left to right: Marie Marshall - Research Sister, Jennie Smith - Clerical Officer, Lizzy Bell - Data Coordinator, Maqsood Khan - Research Charge Nurse, Professor Michael Cork - Chief Investigator, Les Hunter - Research Administrator, Karen French - Head of Operations.

(June 2017)

Neonatal MRI scanner research study featured in national press

Doctors in Sheffield are pioneering the use of a compact MRI scanner for imaging the brains of premature babies.

The machine, at the Royal Hallamshire Hospital, is one of only two purpose-built neonatal MRI scanners in the world.

At present, ultrasound is normally used to scan the brains of newborns.

Prof Paul Griffiths, of the University of Sheffield, said MRI was better at showing the structures of the brain and abnormalities more clearly. 

Read more at the links below 

 BBC News 

Telegraph Science

News at 10 (video - item starts 23 minutes in)

BBC Radio 5 Live (item starts 2.25.20 in)

Science World Report

Sheffield Telegraph

The Star

Health Medicine Network

True Viral News

Healthcare Asia

Science Focus

The Independent

Medical News

Qatar Tribune

Counsel & Heal

(January 2017)

CRF study features in national press

A CRF supported study of stem cells following stroke featured in the Daily Mail during December 2016.

(December 2016)

Sheffield researchers awarded £3.1m funding to pioneer new drugs and treatments

RESEARCHERS at Sheffield Teaching Hospitals and the University of Sheffield have been awarded £3.1 million to continue to pioneer new drugs and treatments that may one day transform patient care.

The funding, announced by the Department of Health and the National Institute for Health Research (NIHR), will enable even more patients to take part in groundbreaking research at the Royal Hallamshire and Northern General Hospital’s dedicated Clinical Research Facility. 

Sheffield was one of only 23 research centres across England awarded funding, which will see its status as a designated NIHR Clinical Research Facility renewed for a further five years. Click here to read more and click here to watch a short video presentation about the CRF facilities on offer in Sheffield. You will need to enter the password to view the video. The password is CRF

(November 2016)

Patients more likely to survive in research-active hospitals

A study, supported by the National Institute for Health Research (NIHR) Clinical Research Network (CRN), has found that bowel cancer patients are more likely to survive in research-active hospitals.

Even patients who are not involved in the trials themselves benefit from being in hospitals where a large amount of clinical research is taking place. Click here for more details.

(November 2016)

League table reveals 100% of NHS trusts are research active

The 2015/16 National Institute for Health Research (NIHR) Clinical Research Network (CRN) NHS Research Activity League Table has published and it shows all NHS trusts in England are delivering clinical research, providing thousands more patients with access to better treatments and care.

The Table can be accessed here. It provides a picture of how much clinical research is happening, where, in what types of trusts, and involving how many patients.

Promoting, conducting and using clinical research to improve treatments for patients is part of the NHS England Constitution.

(October 2016)

Professor Named in 'Most Highly Cited of 2017' Listing

Professor Rob Storey, Professor of Cardiology at Sheffield Teaching Hospitals has been named in the ‘most highly cited of 2017’ listing prepared annually by Clarivate analytics. The list recognises leading researchers in 21 fields of the sciences and social sciences from around the world. To receive this accolade, Professor Storey’s research has been ranked in the top 1% by citations for clinical medicine during the period 2005-2015. Professor Storey is a world-leading expert on antiplatelet strategies for acute coronary syndromes.  

(Dec 2017)

Major New International Text Book Led by CRF PI

Dr Ever Grech, Consultant Interventional Cardiologist has edited and led the third edition of 'Practical Interventional Cardiology'. 

The textbook includes 14 chapter contributions from interventional cardiologists based at the Northern General Hospital’s South Yorkshire Cardiothoracic Centre – the largest contribution of any centre in the world.

Click here to read more

(Oct 2017)

CRF Research Nurse Maqsood Khan Features in BBC 1 Inside Out Programme

The piece features ground breaking clinical research in eczema which was supported by the CRF and overseen by Professor Mike Cork. The item begins at 1 minute and is available for 30 days after 2nd October 2017. Click here to watch the film while there is still time! 

For information on clinical research studies available to participate in nationwide please visit the UK Clinical Trials Gateway at

 (October 2017)

'Next Generation’ Device Could Herald Breakthrough in Prediction of Preterm Birth

A NEW ‘next generation’ device which could help doctors reliably predict the risk of preterm birth is to be developed by Sheffield Teaching Hospitals NHS Foundation Trust and the University of Sheffield thanks to funding from the National Institute for Health Research (NIHR) and the Medical Research Council (MRC). 

To watch a short video and learn more click on the picture below.

(August 2017)

Welcome to the Sheffield Biomedical Research Centre

The Sheffield NIHR BRC is a partnership between Sheffield Teaching Hospitals NHS Foundation Trust and the University of Sheffield. It is dedicated to improving the lives of patients living with neurological diseases by conducting neuroscience research for chronic neurological disorders. 

The focus of research at the BRC is around neurodegenerative diseases (such as Alzheimer's, dementia, Parkinson's and motor neuron disease), neuroinflammation (such as seen in multiple sclerosis) and cerebrovascular disease  (including prevention, earlier diagnosis and improved treatment of stroke). 

The CRF and BRC will be working very closely together to ensure that Sheffield stays at the forefront of translational neuroscience.

You can find out more about the BRC by watching a short video presentation here.

(June 2017)

Researchers and patients showcase medical advances of the future

Researchers from Sheffield Teaching Hospitals NHS Foundation Trust showcase how medical research makes a difference to NHS patients' lives at a special event held at the Northern General Hospital Medical Education Centre on Monday 6th February.

Click here to read more about the day which included a presentation from CRF Director, Professor Chris Newman.

(February 2017)

New report highlights the benefits to the UK economy of clinical research

Government support for clinical research contributes to the UK economy, creates jobs and helps NHS finances go further, a new report shows. Click here to read more

(December 2016)

£750,000 grant to help children who have lost limbs

 Devices for Dignity, hosted by Sheffield Teaching Hospitals NHS Foundation Trust, to lead £750,000 national initiative to help clinicians, academics and industry partners develop state-of-the-art child prosthetic devices.

Announced by Health Secretary Jeremy Hunt, the national Child Prosthetics Research Collaboration will bring together clinicians, academics and industry partners so that innovations and research into child prosthetics can be brought to the NHS more quickly and to greater scale. Click here to read more.

(November 2016)

UK’s largest renal clinical trial reaches patient recruitment target

Kidney Research UK and King’s College Hospital, London are delighted to announce that the number of dialysis patients now recruited onto the four-year PIVOTAL clinical trial has reached the nationwide target of 2,080. The research team at Sheffield Teaching Hospitals and our own CRF Clinical Research Nurse, Yvonne Jackson have received thanks for their outstanding contribution to this complex national study from the Sponsors.

One of the complications of being treated for kidney failure using haemodialysis is that people develop anaemia which can leave them feeling exhausted and seriously reduces quality of life. Patients are already given intravenous iron to treat the condition, but there is limited consistency across the NHS as to how much is administered.The PIVOTAL trial is facilitated and funded by Kidney Research UK through an unrestricted grant from Vifor Fresenius Medical Care Renal Pharma Ltd. More information can be found here.

(August 2016)

Sheffield Consumers in Healthcare Research free event

A free event aimed at anyone who wanted to find out more about patient and public involvement in research and the work done in this area at Sheffield Teaching Hospitals NHS Foundation Trust was hosted by the Sheffield Clinical Research Office and CRF staff were present. This event is held each year in May. Watch this space for more information about the next meeting due in May 2017 in collaboration with the University of Sheffield Festival of Arts and Humanities.

Jessop Wing Big Knit

On April 19th the Clinical Research Office organised an event to gather knitters together to knit hats for newborn babies. Our clinical research midwives sat with the knitters to take the opportunity to highlight clinical research taking place in obstetrics and neonatology. The day was a great success and the research had radio coverage on and off all throughout the day on BBC Radio Sheffield.

It was such a success we now have 304 baby hats and plans for the knitting group to meet regularly! If you are interested in joining why not come and find the CRF stand at the evening event to celebrate International Clinical Trials Day on Friday May 20th a the Circle, Rockingham Lane in Sheffield City Centre?

(May 2016)

Sheffield Teaching Hospitals Chief Nurse on New Year Honours List

Professor Hilary Chapman, chief nurse at Sheffield Teaching Hospitals NHS Foundation Trust, has received a damehood for services to nursing in the Queen’s New Year Honours (2018). 

Hilary is one of the country’s most prominent Chief Nurses, and has made major contributions to health policy, healthcare delivery and system reform.

Click here to read more

(Dec 2017)

Leading Research into Pulmonary Hypertension

Professor David Kiely, Director of the Sheffield Pulmonary Vascular Disease Unit has won the award for outstanding research leadership in the NHS.

Professor Kiely and his team have participated in more than 40 studies, resulting in drugs that are now used to treat pulmonary hypertension. Collaborating with colleagues in other specialties in Sheffield, the team has pioneered PH diagnostic techniques such as MRI, which has replaced a number of invasive tests, making it safer and more comfortable for patients. 

Click here to read more

(Oct 2017)

Sheffield Motor Neuron Disease Patient Features on BBC Inside Out Programme

Professor Dame Pamela Shaw, Vice-President and Head of the Faculty of Medicine, Dentistry and Health at the University of Sheffield, discusses motor neurone disease (MND) as the battle of MND sufferer Ian Pratt is featured.

Click here to watch the feature, which begins at 14.35 on the scroll bar. It is available for 28 days after the 9th of October.

 (October 2017)

CRF Manager Karen French Features in UK CRF Network Newsletter

Karen is featured as part of an interview about how using tools designed by the UK CRF Network has helped the NIHR Sheffield Clinical Research Facility to support collaborations with Industry partners. 

(September 2017)

International Acclaim for Leading Gluten Expert

 Professor David Sanders, consultant gastroenterologist at Sheffield Teaching Hospitals NHS Foundation Trust and Professor of Gastroenterology at the University of Sheffield, has been awarded the prestigious Bengt Ihre Medal from the Swedish Society of Gastroenterology. 
The international award, which is one of the most prestigious in the field of gastroenterology, has only been awarded to UK gastroenterologists on three previous occasions in its history.   
Click here to read more.

(July 2017)

Are you Yorkshire fit?The Yorkshire Health Study

The Yorkshire Health Study is the largest long term health study in Yorkshire.

Since 2010, over 30,000 people have filled in their Health Questionnaire.

You can watch a video updating on progress with the study here

If you live in Yorkshire and are over 16 you are eligible to take part. It only takes 10 minutes! Visit their website here 

 (June 2017)

An additional brain scan could provide more certainty in diagnosing foetal brain abnormalities

An additional MRI scan during pregnancy could help to more accurately detect foetal abnormalities and give more certainty for parents whose 20-week ultrasound scan showed a potential problem, according to new research funded by the NIHR at taking place at Jessop Wing. Click here to read more.

February 2016

Christmas stocking gifts from the Jessop Wing knitters

Following the success of the ‘100 hats for 100 babies’ event hosted in April 2016 as part of the University of Sheffield Life Festival (see the news story later on this page), the Jessop Wing knitters have been meeting every month and continue to knit essentials such as hats and blankets for the neonatal unit, as well as the little Christmas stocking gifts pictured here.

The group are currently sourcing patterns and looking for ideas for an Easter knitting theme. 

If you can donate yarn to the group or would like to join the friendly group which meet monthly please contact Sheila Duffy on 0114 2268333. 

(February 2016)

Sheffield scientists and doctors set to get million pound boost for cancer research

Sheffield scientists and doctors are set to receive nearly one million pounds from Cancer Research UK and the National Institute for Health Research over the next five years to continue their ground-breaking work at the Sheffield Experimental Cancer Medicine Centre (ECMC).

In Sheffield, the ECMC is a collaboration between the clinical trials unit based at Weston Park Cancer Hospital, part of the Sheffield Teaching Hospitals NHS Trust, and scientists at the University of Sheffield. Read more by clicking here.

(December 2016)

Research could offer hope to hundreds of women resorting to surgical measures to control menorrhagia

 Women could be spared surgery that risks their fertility by a simple test for blood-clotting disorders which could then be treated by taking a pill or using a nasal spray, according to new research. 

Each year 30,000 women in England and Wales aged 30 to 50 have a hysterectomy – surgical removal of the womb – or a procedure called endometrial ablation, which burns away parts of the lining of the womb in order to end debilitating heavy monthly bleeding.

 But now a ground-breaking study carried out by specialists at Sheffield Teaching Hospitals NHS Trust suggests that more than 20 per cent of these patients may suffer from blood-clotting disorders.

The story has been featured in the Mail Online and can be accessed here. It has also featured in the Yorkshire Post and can be accessed here.

(November 2016)

Sheffield health care is best in Yorkshire

The local media has featured the hard work and commitment of Trust staff to achieve the overall rating of ‘Good’ by the Care Quality Commission with many services rated as ‘Outstanding'. The coverage includes a two page feature in the Sheffield Star, as well as the Sheffield Telegraph and a drive time interview on BBC Radio Sheffield.

 This means that people in Sheffield are getting some of the best health care in the country – and the very best in Yorkshire. Following the rating, the trust’s 16,000 staff and volunteers have been celebrating their status, which puts them in the top 30 per cent nationally. Dr David Throssell, the Trust Medical Director was interviewed about the CQC rating by BBC Radio Sheffield presenter Howard Pressman on the drive time show. To listen to the interview please click here (Interview begins at 01:39:41).

(June 2016)