Publishing? The following disclaimer is requested by the NIHR…

This is a summary of independent research funded by [name of research funder] and carried out at the National Institute for Health Research (NIHR) Sheffield Biomedical Research Centre (Translational Neuroscience) / NIHR Sheffield Clinical Research Facility  [delete as appropriate]. The views expressed are those of the author(s) and not necessarily those of the [name of research funder],  NHS, the NIHR or the Department of Health.

Why use the NIHR Sheffield CRF?

"I wanted to extend a HUGE thank you for your hard work in delivering the study. I was amazed at how quickly everything came together, how well you all worked together and how smoothly the visits all went. I am really impressed by the professionalism and team work"

The Clinical Research Facility (CRF) provide a specialist environment, at both the Royal Hallamshire Hospital and Northern General Hospitals, for the conduct of high quality clinical research. Patients and healthy volunteers are guaranteed that research undertaken in the CRF has met all the legislative, governance and ethical requirements that ensure participant safety. The CRF Manager, Lead Nurse and Research Matrons, along with their team of clinical and administrative research support staff, work extensively with Investigators to ensure full use of CRF resources.

The CRF is a resource open to researchers from all clinical disciplines encouraging collaboration with researchers across South Yorkshire

The CRF offers dedicated space to investigators undertaking all types of clinical research including industry and experimental medicine studies. The Facility has the capacity to care for participants on a daily and overnight basis. The CRF has the range of expertise required to run complex studies with small numbers of patients as well as large healthy volunteer studies where the recruitment of hundreds of people is necessary. The CRF can also provide an outreach service for studies which depend upon delivering in their own clinical environment.

Accelerating delivery of clinical research during 2016/17

Between April 2016 and March 2017 the CRF achieved the following successes which contributed to the acceleration of clinical research in Sheffield and beyond:
 Description of Achievement How often this was achieved during 2016/17
 Highest recruiter 3 occasions
 First global recruit 1 occasion
 First UK recruit 3 occasions
 First study patient dosed 1 occasion
 First patient screened globally 1 occasion

"Your study site has randomised both the 1st and 2nd UK patients into the study and you are currently the country’s top recruiter. I would sincerely like to thank you, not only for moving swiftly following site initiation to identify and approach potential patients, but for your hard work in consenting, screening and randomising those first 2 patients in December just a few days before Christmas. It’s really encouraging to see that you’ve made such a strong start to recruitment"


Are you considering applying for a Research for Patient Benefit (RfPB) Grant? 

The Reseach Design Service Yorkshire and the Humber (RDS YH) is holding an NIHR Research for Patient Benefit (RfPB) information session on Tuesday 10 October in Sheffield. This is a half day event, aimed at researchers in the Yorkshire and Humber region, to promote understanding of the requirements and scope of NIHR’s Research for Patient Benefit (RfPB) programme from the perspective of RfPB panel members.  It will provide information about RfPB and about the types of proposals that the programme is looking for. The event is FREE and refreshments will be provided 

Click here to see the event flyer which includes information on how to book a place.

Research Design Service Grant Writing Workshops: Developing your research idea into a high quality grant application

Research Design Service Yorkshire and Humber (RDS YH) will hold FREE one-day grant writing workshops in Leeds, Sheffield and York.  The workshops are aimed at researchers in applied healthcare who are interested in submitting a grant application to NIHR. To get the most out of the workshop, we recommend that you come with a research question for a proposal that you personally would like to develop.  

Who should attend?
If you are a first time applicant, have been unsuccessful with an NIHR application in the past or you simply want to understand what makes a good grant application then attending this workshop will help.
The workshop will provide practical and contextual advice to answer the following questions:

  • What do NIHR and funding panels look for in a research proposal?
  • What should you be thinking about at the outset (is my idea unique, needed and/or a priority for NIHR or the funder?
  • How do I frame a research question?
  • What are the key elements of a strong funding proposal?
  • What should my research team look like?
  • Who do I need to involve (public involvement, user involvement, specialist involvement etc.)?
  • What is involved in study design?
  • How can I make sure I can deliver if I'm successful?
  • How do I think about impact?
Workshop dates:
Thursday 9 February,
Wednesday 17 May, Sheffield
Wednesday 27 September, York

For more information contact Rose Cliff: 0114 22 20828 or email:

Are you aware of current funding opportunities?

To find out more about what current funding opportunities are available from NHIR click here.

If you are considering developing an application the NIHR RDS YH offers free support or specialist advice to turn your ideas into research proposals or to further develop your existing proposals. For more information or to book an appointment please click here.

For University of Sheffield staff, the Research & Innovation Service has faculty support teams that provide assistance at every stage of the research grant application process. Your relevant Research Strategy Manager and Research Development Officer will be happy to offer advice and support in the early stages of a project. For further contact details please see the R&IS website.

Have you used the CRF to deliver your research?

"It has been an exceptional experience working with you and the entire CRF team. We have together transformed the lives of these patients for ever. Your enthusiasm and commitment and that of the entire team has been brilliant."

Please take a moment to give us your feedback on our service so that we can be sure to provide high quality support in the way that you need us. 

It will only take a few moments of your time and the information you provide will be used to improve our current service and to shape the service of the future, making sure that we can support your research in the way you need us.
Click here to go to a short feedback survey.


Collaboration from Concept to Care

Sheffield Teaching Hospitals NHS Foundation Trust works closely within a network of partner organisations to build collaborations and help develop research ideas.

Additional Information for researchers which may be helpful can be found at the Sheffield Clinical Research Office 

The University of Sheffield works with Sheffield Teaching Hospitals NHS Foundation Trust to build clinical and academic partnerships. For help finding academic collaborators or to discuss potential grant funding for a research project the University of Sheffield can be contacted via the University of Sheffield Healthcare Gateway.

The NIHR Research Design Service for Yorkshire and Humber (RDS YH) provides advice and support to applied health and social care researchers to help them to develop and design high quality research proposals for submission to NIHR and other national, peer-reviewed funding competitions. Support is provided free of charge.

Support is also available to assist you in finding members of the public to assist you in planning your research via the website People in Research



Accessing and Using the CRF