The NIHR Sheffield Clinical Research Facility

The National Institute for Health Research (NIHR) Sheffield Clinical Research Facility (CRF) is based at Sheffield Teaching Hospitals, on O Floor of the Royal Hallamshire Hospital and on the first floor of the Centre for Biomedical Research at the Northern General Hospital. It has the facilities you find on a ward or out-patient clinic and is run by expert, qualified staff such as doctors and nurses.

The CRF recruits patients into clinical trials everyday.  Taking part in a trial might mean having an extra blood sample taken or completing a life-style questionnaire. Not all clinical trials involve testing drugs. Trials often provide evidence for more efficient ways of providing healthcare and improving how we treat our patients. Everything is explained in advance to help you decide whether to take part. This is always your decision; there is no obligation and and you can change your mind at any time. Your decision will not affect your normal medical care. 

Without the valuable contribution made by patients and members of the public, advances in healthcare simply would not be possible. Participating in a clinical trial or being involved in the research process helps us all to live healthier lives.

Advances in our knowledge of disease and good healthcare practices are happening here in Sheffield, not just in global capital cities. Our patients tell us that it can be a very rewarding experience to know that you have been a part of healthcare advancements. Click here to open a poster with more  information about why people take part in clinical research across the UK.

We work hard to provide a welcoming environment.  Everyone participating in clinical research at the CRF is guaranteed that the research we undertake has met all the legislative, governance and ethical requirements that ensure safety.


Are you interested in getting involved in research, or finding more out about what it might involve?

You can read about recent events and upcoming opportunities to get involved in clinical research in the NIHR Patient and Public Involvement Newsletter here




Sheffield research participants explain how clinical trials help patients

A diabetes patient and Sheffield resident says it is essential people put themselves forwards for clinical research to help towards providing better treatments for conditions such as her own. Read the Sheffield Star article here



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We welcome your feedback on our website and value your ideas about how to improve it. Click on the 'Feedback on the CRF' picture below and you can complete a short survey or contact us directly.


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